Thursday, 9 October 2014

First Ebola, Now Marburg. How Do We Stop Future Outbreaks?

Marburg, a virus similar to Ebola, has hit the radar in the African country of Uganda, raising concerns about another deadly outbreak. With two lethal viruses threatening public health, many are questioning why these contagions seem to be flaring up more often—and more important, what we can do to avoid them in the future?
The current Ebola outbreak originated in West Africa and has killed 3,439 people, more than all other past outbreaks combined. The first Marburg death was confirmed recently in Kampala, Uganda. Both are hemorrhagic fevers passed from animals to humans, which has experts examining how humans and the African wildlife interact.
One mystery surrounding these viruses is where they live between outbreaks, when they aren’t infecting humans, author and Ebola expert David Quammen told National Geographic. For example, health officials know Ebola likely goes dormant in an animal, called its “reservoir host,” but they have yet to identify exactly which species. At least one of the suspects is the fruit bat, which is believed to host several other viruses (including Marburg and SARS) without getting sick. These bats usually live in large, tightly packed groups, allowing the virus to spread easily among the animals.
In the past, there was enough room in Africa for humans and fruit bats to exist without much contact. Deforestation has changed this, according to an editorial in The Guardian. West Africa was once covered in rain forests, a common habitat for fruit bats. During the past decade, loggers have stripped the land, reducing the habitable area for the animals. Laws governing more responsible logging practices in that part of the world could help reduce the risk of future outbreaks, but civil wars and political corruption are slowing progress.
As the forests shrink, the mining industry has been moving more people into Africa to tap its vast mineral reserves. These miners often have to travel through high concentrations of bats, which increases the likelihood of someone being infected. Like the rain forests, mines are also popular habitats for animals that might carry these viruses, and miners have been among the victims in several Marburg outbreaks in the past. In 1998, one of the largest natural Marburg outbreaks to date occurred in the Democratic Republic of Congo, in an area pocked with several illegal gold mines. During the course of the epidemic, there were 149 cases and 123 deaths. Miners were found to be at a significantly higher risk of contracting Marburg than the general population, suggesting they may be more frequently exposed to the areas in which reservoir hosts live.
But animals in the wild are not the only threat to spread these viruses; wild animals — including primates, birds, and reptiles — captured and sold for food or as exotic pets are also a risk. Some experts believe the illegal wildlife trade market — which brings in between $10 and $20 billion each year — is one of the greatest threats due to its global reach and the lack of health standards. “As wildlife is traded between hunters, middle marketers, and consumers, there are, quite literally, billions of opportunities for disease transmission among wildlife, humans, and domestic animals,” wrote Timonty Bouley and Sara Thompson for The World Bank. Research has found that outbreaks resulting from wildlife trade have caused hundreds of billions of dollars of economic damage globally. It has been such a problem the researchers suggested that eradicating the illegal trade market would be more practical and effective at stopping outbreaks than attacking the virus directly.

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